There were no correlation between ghrelin, leptin and obestatin hormones and body composition variables except for significant inverse correlation between obestatin and BCM (r=-0.40, P=0.03) and FFMI(r=-0.40, P=0.029) in CKD patients (figure 1 and 3 in comparison with figure 2 and 4 in the controls). This evidence concerns the gene LEP and chronic kidney disease.