However, current data on the association between VEGF +936 C/T and breast cancer susceptibility have shown a great discrepancy.15-26 Most importantly, the overall evidence of several meta-analyses, in which the included data are under intensive debate, suggested the association of +936 C/T polymorphism and breast cancer risk is not statistically significant.27-31 These findings seem to contradict the experimental evidence supplied in previous research. This evidence concerns the gene VEGFA and breast carcinoma.