AGTR1 and fetal growth restriction: 2010), while maternal diet-induced LBW decreased methylation of the AT1R promoter in the adrenals (Bogdarina et al. 2007). Intrauterine growth restriction (IUGR) has been shown to affect histone modification in organs such as the liver (Tosh et al. 2010) and lungs (Joss-Moore et al. 2010), but so far, the status of histone modifications in the heart has not been reported.