A pathway enrichment analysis using InnateDB [52] revealed that the THP-1 cells show distinct signs of infection (Table 2) since we identified numerous enriched pathways involved in immune response such as IFN-α/β signaling, IFN-γ signaling and RIG-I/MDA5-mediated induction of IFN-α/β pathways. Here, RIGI is linked to infection.