CCR6 and dermatitis: The latter finding is interesting because CCR6, whose ligand CCL20 is expressed by epidermal keratinocytes, endothelial cells, and dendritic cells during skin inflammation, has been shown to play an important role in promoting the infiltration of activated T cells into the skin [13]; thus, CCR6 expression may imply that the dermal γδ T cells largely represent previously activated cells that have been recruited to the skin.