S100A8 and B-cell non-Hodgkin lymphoma: Transgenic mice expressing wild-type CagA but not tyrosine-phosphorylation-resistant CagA developed gastric and small intestinal epithelial hyperplasia and neoplasia and B cell lymphomas and myeloid leukemias [38], supporting a critical role of CagA tyrosine phosphorylation in H. pylori-induced oncogenesis.