LHB and hepatocellular carcinoma: The W4P variation was related to HCC; therefore, we examined whether the variation was implicated in cell growth using mouse NIH3T3 cell lines constitutively expressing WT LHB (WT-LHB-NIH3T3) and W4P variant LHB (W4P-LHB-NIH3T3) (Additional file 2: Figure S2).