KLF4 and acute lymphoblastic leukemia: To exclude the possibility that the effects of KLF4 on Jurkat cells were cell line-specific, we next tested whether KLF4 could induce apoptosis in MOLT4 or CCRF-CEM cells, which are two γ-secretase inhibitors (GSI)-resistant T-ALL cell lines [22] and expressed minimal KLF4 (Additional files 1 and 2: Figure S7).