While this increase was also matched with an increase in TREM1 gene expression from the sorted PMNs of RA patients by real-time RT-PCR (Fig. 1D), it did not correlate with an increase in surface receptor expression per cell as the MFI levels remained similar and were not statistically different (average values shown in Fig. 1C). The gene discussed is TREM1; the disease is rheumatoid arthritis.