ADAM33 and asthma: Other inflammatory mediators, which play a role in asthma, include matrix metalloproteinases (MMP), including MMP-9 and ADAM-33 (a disintegrin and metalloproteinase-33); chemokines including eotaxins, RANTES, and MCP-1; chemokine receptors, CCR-3 for eotaxin, CCR-5 for RANTES, and CCR-2 for MCP-1 [3, 4].