According to the GWAS annotations of Johnson and O’Donnell (2009), the latter two of the three SNPs were associated with “type II diabetes mellitus,” which was in good accordance with the recent reports showing that PVT1 may contribute to diabetic nephropathy (Hanson et al., 2007; Alvarez and DiStefano, 2011; Alwohhaib et al., 2014). Here, PVT1 is linked to diabetic kidney disease.