SHPRH and cancer: The protein coding genes ZNRD1, RNF39 and PPP1R11, along with the ncRNA ZNRD1-AS1, have been associated with disease states that are related to autoimmunity, immunity, and infection; while EPM2A and SHPRH have been associated with glycogen metabolism, cancer, and chemical dependency (Hindorff et al., 2013; Becker et al., 2013).