In this study, we investigated the expression of FilGAP, with reference to the status of its associated molecules, including FLNa, integrin β2, epithelial cell transforming factor 2 (ECT2), and Rac1, in FL, diffuse large B-cell lymphoma (DLBCL), and peripheral T-cell lymphoma (PTCL). This evidence concerns the gene RAC1 and mature T-cell and NK-cell non-Hodgkin lymphoma.