CDKN1B and non-small cell lung carcinoma: We found that miR-221 and miR-222 only occasionally suppressed p27Kip1 and p57 expression in NSCLC cells (Fig. S14), suggesting that suppression of p27Kip1 and p57 expression may not be solely responsible for impaired G1/S checkpoints that lead to the increased S-phase population in cells transfected with miR-221 or miR-222 in NSCLC cells.