Similar data have been obtained in the case of caerulein-induced pancreatitis, where TRPA1 antagonists and genetic removal of TRPA1 (TRPA1 KO mouse) have been shown to reduce the extent of inflammation and pain in this model (Ceppa et al. 2010; Schwartz et al. 2011; Schwartz et al. 2013). The gene discussed is TRPA1; the disease is pancreatitis.