KIF5A and myeloid sarcoma: Mutations in the KIF5A gene have been linked to hereditary spastic paraplegia (Reid et al., 2002; Musumeci et al., 2011), and its downregulation has been associated with axonal transport defects in models of multiple sclerosis (MS; Kreutzer et al., 2012), Alzheimer's disease (Stokin et al., 2005), and Parkinson's disease (Chu et al., 2012).