Inflammatory infiltrates were wider in both Calu-6 and SK-MES tumors from hrIL-27-treated mice than in control tumors, because of the significant (P < 0.05) increase in their granulocyte and macrophage content, along with cancer cell expression of CXCL3 (Figure 2C and 2D) (Table 3). The gene discussed is CXCL3; the disease is cancer.