Three ATP-binding cassette (ABC) drug transporters have been associated with drug resistance in most cancers [55], and the ABCB1 (p-glycoprotein/MDR1), ABCC1 (MRP1) and ABCC2 (MRP2) subfamilies have been shown to be involved in the development of cisplatin resistance [56–59]. The gene discussed is ABCC2; the disease is cancer.