Quantitative analysis revealed that the TUNEL-positive cells (per 400X fields) were significantly less abundant in the Iov+renalase group (16.7±3.0) than that in the Iov+Veh (29.1±2.5) groups (P<0.05), as shown in Fig. 2. In comparison, renalase preconditioning reduced the tubular apoptosis in rats with CIN (Fig. 2A and 2B). The gene discussed is RNLS; the disease is cervical squamous intraepithelial neoplasia.