However, we found no association between the TNF-alpha (−308 G/A) polymorphism and PCOS risk in the overall population (A vs. G: OR = 0.93, 95% CI = 0.77–1.11; AA vs. GG: OR = 0.61, 95% CI = 0.26–1.41; GA vs. GG: OR = 0.89, 95% CI = 0.65–1.23; AA + GA vs. GG: OR = 0.85, 95% CI = 0.63–1.16; AA vs. GA + GG: OR = 0.66, 95% CI = 0.29–1.49). The gene discussed is TNF; the disease is polycystic ovary syndrome.