IL6 and polycystic ovary syndrome: Although the relatively limited study number (only two studies for IL-6 (−174 G/C) polymorphism in the subgroup analysis specific to HWE in controls and genotyping method of pyrosequencing) and small sample size might have resulted in the null results, we could not rule out the possibility that the IL-6 (−174 G/C) polymorphism was actually not associated with PCOS risk.