IL6 and polycystic ovary syndrome: In further subgroup analysis based on study sample size, the IL-6 (−174 G/C) polymorphism was significantly associated with a decreased PCOS risk among sample size > 200 in the allelic model (C vs. G: OR = 0.47, 95% CI = 0.28–0.80) and dominant model (CC + GC vs. GG: OR = 0.32, 95% CI = 0.13–0.78), as well as by homozygote comparison (CC vs. GG: OR = 0.38, 95% CI = 0.17–0.89) and heterozygote comparison (GC vs. GG: OR = 0.31, 95% CI = 0.13–0.74).