For every case, there was a statistically significant difference between TCII, TCII-R and Ki-67 expression in malignant tumor tissue compared to that in corresponding adjacent normal tissue (TCII: p<0.0000000000001; TCII-R: p<0.0000000001; Ki-67: p<0.0000000001). This evidence concerns the gene MKI67 and neoplasm.