In order to understand the role of miR-93 on the c-Met/PI3K/PTEN/Akt pathway, we then analyzed the protein expressions of PI3K class 1A and 1B (p85, phospho-p85, p110-alpha, -beta, and -gamma) by western blotting of HCC cells transfected with anti-miR-93. The gene discussed is MET; the disease is hepatocellular carcinoma.