Furthermore, the upregulated genes (PDPK1, EZR, MYO6, CDC42BPA, OPHN1, ARF6 and WASL) identified in the present study that were enriched in the actin filament-based process require further study in order to determine whether they may be used as potential biomarkers of allergic asthma. Here, OPHN1 is linked to allergic asthma.