SVIL and familial dilated cardiomyopathy: We focused on the remaining candidates (USP13, FLNC, SVIL), which, at the time of our study, had no known link to cardiac function but were attractive given that: 1) they were found in loci that had been associated with LVD; and 2) they had high OPEN scores for DCM despite having a small number of genes at their locus.