Overlaying OPEN DCM scores for each of the genes at these loci revealed two promising candidates (Figure 3C): BAG3, a recently identified causal DCM gene [35], and HSBP7, a gene recently implicated in protection against tachycardia-induced CMP [36] and that also caused a reduction in cardiac output upon disruption in zebrafish [11]. Here, BAG3 is linked to familial dilated cardiomyopathy.