SOCS1 and influenza: It would be of interest to the field to examine the role of SOCS1 in other respiratory tract virus infections; of interest, impaired interferon induction has been observed in PBMCs and dendritic cells from patients with respiratory syncytial virus and influenza, respectively.8,9 Recently, Spann et al35 showed higher viral loads in respiratory syncytial virus– and metapneumovirus-infected tracheal epithelial cells from wheezy children, but no impairments in type or type III interferons were observed.35