For example, equilibrative nucleoside transporter-1 (ENT1) antagonists were found to be potent amplifiers of oHSV replication following a drug screening to identify molecules that increased viral spread [109], whilst a chemical library screen for compounds that sensitise cancer cells to viral cytotoxicity revealed a previously unidentified small molecule as a synergistic enhancer of VSV-mediated cell killing [110]. The gene discussed is SLC29A1; the disease is cancer.