Taurine appears to play an important role in protecting against the effects of stress-induced apoptosis, including diabetic vasculopathy, by inhibition of renal lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), which facilitates the uptake of oxidized low-density lipoprotein (oxLDL) and induces endothelial dysfunction [27,28]. The gene discussed is OLR1; the disease is endothelial dysfunction.