NPPB and hypertensive disorder: We found no significant difference in the concentrations of NT-proBNP between hypertensive subjects with LVH and those without LVH, which is in keeping with previous findings.5,24,25 NT-proBNP concentrations were not correlated with LV mass index, interventricular septal wall thickness or posterior wall thickness in diastole, which is similar to other findings.9 This lack of correlation between NT-proBNP and LV mass index might explain why NT-proBNP is not a good marker for differentiating hypertensive LVH from hypertension without LVH and HF.