Previous studies have shown that miyabenol C possesses various functions, such as being anti-proliferative and pro-apoptotic in tumor cells [45, 49], inhibiting the activity of protein kinas C [44, 50], antagonizing human 5-hydroxytryptamine (5-HT) receptor [51], having estrogenic activity through binding to estrogen receptor [52, 53], and having ecdysteroid antagonistic activity in Drosophila cell bioassays [46]. This evidence concerns the gene ESR1 and neoplasm.