In terms of individual cancers, we estimated an OR>1 for the HOXB13 G84E mutation carriers in the following 12 cancer types (out of fourteen) in comparison with controls not diagnosed with any form of (non-melanoma skin) cancer: breast, non-Hodgkin’s lymphoma, kidney, bladder, melanoma, endometrium, pancreas, colon, thyroid, ovary, multiple myeloma, and lung (Table 1). The gene discussed is HOXB13; the disease is plasma cell myeloma.