WNT10A and odonto-onycho-dermal dysplasia: The significance of WNT10A in organogenesis was not recognized until it was discovered that WNT10A mutations can cause Odonto-onycho-dermal Dysplasia (OODD; MIM#257980), a rare autosomal recessive syndrome characterized by sparse hair, severe tooth agenesis, smooth tongue with marked reduction of fungiform and filiform papillae, onychodysplasia, keratoderma, and hyperhidrosis (Adaimy et al.