The Wellcome Trust Case-Control Consortium CHD study demonstrated that the KIF6 719Arg allele is associated with increased risk of CHD only in males [34], which appears to be in agreement with our results, where the KIF6 Trp719Arg polymorphism may only be involved in T2DM and T2DM + CHD development in males as a genetic risk factor for the diseases. This evidence concerns the gene KIF6 and type 2 diabetes mellitus.