RET and Hirschsprung disease: None of the 33 MEN2 patients had consistently evidence of any co-occurring related MEN2 clinical symptoms (pruritic cutaneous lichen amyloidosis or Hirschsprung’s disease), or HPT (serum PTH, Calcium or PTH/calcium rates, and serum phosphate levels ranged in all normal), except one MEN2B patient (F9-II3) had a broad spectrum of pathognomonic nonendocrine abnormalities: a Marfanoid body habitus, tongue mucosal neuromas, lips hypertrophy and CNT.