Although treatment of HDAC inhibitor (TSA) or EZH2 inhibitor (GSK343) alone did not result in any significant re-expression of ABCA1, treatment of demethylating agent, 5aza, alone resulted in a robust re-expression of ABCA1 in CP70 ovarian cancers, suggesting that DNA methylation is responsible for the suppression of ABCA1 in CP70 cells (Figure 1B). This evidence concerns the gene EZH2 and ovarian cancer.