EIF4E and ovarian carcinoma: To comfort these findings overexpression of 4E-BP1 target: eIF4E (eukaryotic translation Initiator Factor 4E) increased Mcl-1 expression and rescued ovarian carcinoma cells from calcium signaling inhibitors + ABT-737-induced apoptosis suggesting that Mcl-1 is crucial for ovarian carcinoma cell survival and that calcium signals act partially through mTORC1 pathway.