Twenty genes in total, all from our DeepSAGE list of 167 significantly differentially expressed genes, were examined; the top 12 based on P-value, 6 further down the 167 gene list based on differential expression in previous HD studies (H2AFY, AQP9, ANXA3, RGS14, ZNF238, NOL3) and another 2 genes from the same list based on possible involvement in HD pathology (CEBPA, TAF15).3, 8, 9, 19, 29, 30, 31 Fluidigm data were analyzed using a linear model as a function of TMS, while accounting for gender and age. The gene discussed is MACROH2A1; the disease is Huntington disease.