Levels of laboratory parameters such as ALT, AST, total and direct bilirubin and HBV-DNA loads were significantly higher in CHB, LC and HCC groups compared to ASYM group whereas the levels of albumin and prothrombin were significantly decreased in LC and HCC groups compared to ASYM and CHB (P < 0.001). Here, ALB is linked to laryngotracheoesophageal cleft.