In endometrial cancer tissues, overexpression of AURKA was significantly higher in non-endometrioid than in endometrioid adenocarcinoma (81 vs. 47%, P=0.026) and in poorly-differentiated (grade 3) tumors compared with well- (grade 1) or moderately- (grade 2) differentiated tumors in endometrioid adenocarcinoma (70 vs. 41%, P=0.005). Here, AURKA is linked to endometrioid adenocarcinoma.