NF1 and neoplasm: Among them, 15 were SDHx-related tumours; 1 tumour, belonging to the Cluster C1A, carried 1 germline and 1 somatic mutation in the FH gene as previously reported13; 2 sporadic tumours from the C2A cluster displayed somatic mutations in NF1; 13 were sporadic tumours with no mutation in known predisposing genes.