SLCO1B3 and cancer: However, in contrast with this presumption, our investigations, along with others, have revealed that Ct-OATP1B3 mRNA expression is strongly associated with cancerous colon and lung tissues, but not with matched normal tissues or hepatocytes, and that Ct-OATP1B3 mRNA is expressed predominantly over Lt-OATP1B3 mRNA in these cancer tissues [5]-[7].