Taken together, although extensive research efforts will be necessary before Ct-OATP1B3 mRNA can be established as a colon cancer biomarker, it is considered likely that such research will be worthwhile to promote in view of the urgent need for diagnostic tools in colon cancer, including the need for the development of a more reliable and less-invasive detection marker for patients in early stages of the disease. This evidence concerns the gene SLCO1B3 and malignant colon neoplasm.