AURKB and melanoma: In Figure 2A cellular morphology after treatment with the Aurora B kinase inhibitor in HBL1 cells is reported and is representative of the marked phenotypical alterations obtained treating melanoma cells with this drug; the incubation with 300 nM barasertib-HQPA (for 3 days) caused the formation of giant cells with irregular shapes, suggesting a failure of cytokinesis [36].