HOXA10 and glioblastoma: Given the apparent central role of HOXA10 in the HOX-signature, X/Y plots for both series of GBM, stratified by CHR7 status, illustrate the correlation between HOXA10 expression alone (Affymetrix probe 214651_s_at) and methylation at the above identified 2 top CpGs (cg05092861, cg01078824) in the promoter of the putative non-coding alternative HOXA10 transcript (NR_037939.1) and in addition at two CpGs (cg18243072, TSS200; cg14625175, exon1) located in the CGI of the promoter of the canonical HOXA10 protein-coding transcript (NM_018951.3) (Figure 4B and C).