Expression data from 473 GBM (TCGA, level 2 Agilent) were used to classify samples into either HOX-high (259) or low (214), based on k-means clustering (Additional file 1: Figure S13), and were annotated with the expression subtype classification, including G-CIMP, and MGMT promoter methylation status [2,24] (Additional file 1: Figure S14). This evidence concerns the gene MGMT and glioblastoma.