WNT5A and gastric cancer: Treatment with the Fab fragment from E. coli expressing clone #16 (Fab16) resulted in the highest inhibition of KKLS gastric cancer cell invasion, which was dependent on endogenous Wnt5a (Supplementary Figure S1A); in addition, Wnt5a expression induced MKN-45 gastric cancer cell invasion and the Fab16 inhibited Wnt5a-dependent invasion (Supplementary Figure S1B).