Although LASP1 showed strong expression throughout the urothelium of the bladder and ureter, a modest overexpression in transitional cell carcinoma (TCC) specimens, the most common type of BC, was observed and the authors depicted LASP1 to be a sensitive biomarker for the presence of TCC in urinary cell pellets (sensitivity, specificity, positive and negative predictive values were determined to be 83.1%, 85.3%, 83.1% and 80.6%, respectively). This evidence concerns the gene LASP1 and transitional cell carcinoma.