LASP1 and breast cancer: Interestingly, nuclear LASP1 localization has a peak in the G2/M phase during proliferation [61] and LASP1 silencing reduces proliferation by cell cycle arrest in the G2/M phase, as shown for BT-20 breast cancer cell line [22], ovarian cancer SKOV-3 cell line [80] and OSCC cell lines [73], indicating a role of LASP1 in cell cycle progression.