ZNF217 and colorectal carcinoma: To explore the potential roles of ZNF217 as a novel prognostic biomarker for CRC and its regulation by miR-203 miRNA in CRC tissues and paired normal colorectal tissues, we performed in vitro experiments and confirmed that 1) ZNF217 can promote proliferation, invasion and migration of CRC cell lines and 2) ZNF217 as well as its effects in CRC cell lines are downregulated by miR-203, hoping to further elucidate the mechanism of CRC development and provide novel findings for targeted treatment of CRC.