HSPB1 and Alzheimer disease: There was also significantly greater HSP27 staining in FTLD compared to AD (P =0.030), control (P =0.009) and MND (P =0.001) for glial cells of the hippocampus, and for granule cells of dentate gyrus in FTLD compared to MND (P =0.002) and control (P =0.007).