HSPB1 and torsades de pointes: However, subgroup analysis between FTLD-tau and FTLD-TDP groups, between FTLD-MAPT and FTLD-Pick groups, and between FTLD-TDP type A, B and C groups, all showed no significant differences in the severity of HSP27 rating values, except for significant differences between FTLD-tau and FTLD-TDP groups for grey matter glial cells of the frontal cortex (P =0.006).