CCN1 and esophageal squamous cell carcinoma: In this study, to investigate the role of TAMs in ESCC, we extracted the upregulated genes reported as M2 genes in MΦ-like THP-1 cells by conditioned medium of ESCC cell line with a cDNA microarray analysis as described.19 Among the genes, CYR61 was induced in TAM-like THP-1 cells.