The clinical phenotype of germline GATA2 mutations include, but is not limited to, spectrum of immune deficits such as MonoMAC syndrome 44–46, dendritic cell, monocyte and lymphoid deficiency (DCML) 47, familial MDS (myelodysplastic syndrome)/AML (acute myeloid leukemia), and Emberger's syndrome 48. This evidence concerns the gene GATA2 and acute myeloid leukemia.