Among patients without history of cardiovascular and renal diseases, compared to insulin group, patients in the EBID and EBID + insulin group had a 77% (HR CI: 0.06, 0.95) and a 55% (HR CI: 0.28, 0.85) reduced risk of MI, respectively, after adjusting for covariates (Table 3). The gene discussed is INS; the disease is kidney disorder.