Indeed, recently, a clinical study reports that BP control by β-blockers is associated with the lower prevalence of sexual dysfunction, independent of age, cardiovascular disease, and medical treatments and that beneficial effect of BP control is greater in older patients.4 Although some data showed that angiotensin II antagonists might be beneficial for erectile function and sexual activity [5, 6], there are no good direct data to recommend a specific class of cardiovascular drug to improve sexual function in patients with cardiovascular disease [1]. The gene discussed is AGT; the disease is cardiovascular disorder.